329: CELL BIOLOGY: Does Notch Take the Sweet Road to Success? -- Lowe 307 (5715): 1570
Given that Notch is crucial for animal development, it is not surprising that elaborate mechanisms have evolved to control expression of the Notch gene. … Okajima et al. unveil a new mechanism for controlling Notch expression, which depends on regulating the amount of Notch at the cell surface.An evolutionarily conserved signalling pathway in animals. Common descent, stabilizing selection.